| Echinatin | |||||||
| Catalogue number: | HE042680 |
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| Chemical name： | 3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | ||||||
| Synonyms： | Echinatin | ||||||
| CAS number: | 34221-41-5 |
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| Purity(HPLC): | 98% | ||||||
| M.F: | C16H14O4 | ||||||
| M.W: | 270.27 | ||||||
| Appearance: | Off-white powder | ||||||
| Plant sources: | Glycyrrhiza uralensis lish | ||||||
| Storage temp: | 2～8℃ | ||||||
| Package: | 20mg per bottle;100mg per bottle;1g per bottle | ||||||
| Applications: | |||||||
| For laboratory research use only | |||||||
| Detailed description | |||||||
| 1.Echinatin disturb the mitochondrial energy transfer reactions
and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. 2.Echinatin dose-dependently inhibited LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells. Echinatin was demonstrated to inhibit the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. |
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| References | |||||||
| Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice. | |||||||
| Baoji Herbest Bio-Tech Co.,Ltd No 8 Road, Baoji City shannxi provience China |
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| Email: sales@herbest.cn | |||||||
Echinatin is extracted from the root of Glycyrrhiza glabra L. It inhibits DNP-ATPase activity while stimulating range latent ATPase activity in the low concentration. It disturbs the mitochondrial energy transfer reactions and membrane permeability. Echinatin
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